Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Octacalcium phosphate coating for 3D printed cranioplastic porous titanium implants
|
15.02.2020 |
Smirnov I.
Deev R.
Bozo I.
Fedotov A.
Gurin A.
Mamonov V.
Kravchuk A.
Popov V.
Egorov A.
Komlev V.
|
Surface and Coatings Technology |
10.1016/j.surfcoat.2019.125192 |
0 |
Ссылка
© 2019 Elsevier B.V. In the present study, porous three-dimensional (3D) printed titanium (Ti) implants of complex shape and predefined architecture were produced by selective laser sintering (SLS) technique. Electrochemical deposition combined with biomimetic approach was applied to low-temperature coating of these implants with metastable octacalcium phosphate (OCP) achieved via chemical transformation of dicalcium phosphate dehydrate (DCPD). X-ray diffraction (XRD), Scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and compressive strength analyses were applied to study the chemical composition, morphology and mechanical properties of the final OCP coating on the titanium surface. In vivo comparative study of the porous 3D printed Ti and OCP coated Ti implants has been performed using critical-size crania model, porous 3D printed Ti and coated implants were compared. A statistically significant difference in the newly formed bone thickness for OCP coated Ti implants was detected already at 6 weeks after implantation. Our results provide an experimental proof of a new concept of OCP coating for cranioplasty clinical applications.
Читать
тезис
|
Ultrasound examination of cranial sutures as a method for Craniosynostosis diagnosis in children
|
01.09.2019 |
Sufianov A.
Sadykova O.
Iakimov I.
Sufianov R.
|
Pediatriya - Zhurnal im G.N. Speranskogo |
10.24110/0031-403X-2019-98-5-40-46 |
0 |
Ссылка
© 2019, Pediatria Ltd. All rights reserved. Skull computed tomography (CT), recognized as the «gold standard» in the diagnosis of craniosynostosis (CS), has a significant drawback associated with radiation exposure. The use of ultrasound in the imaging of cranial sutures is a possible research method, replacing CT. Objective of the research: To assess efficacy in CS diagnosis and postoperative observation of children after endoscopic cranioplasty. Materials and methods: The study includes analysis of ultrasound data of cranial sutures in 45 children aged 4,5±1,2 months (from 1,5 to 12 months), which were examined and treated at the Federal Center of Neurosurgery. Ultrasound of cranial sutures was performed on an expert class device. To assess cranial sutures condition authors developed a simple algorithm and an ultrasound protocol, according to which the study was performed. Additionally, all children underwent CT with skull volumetric reconstruction. Results and discussion: According to cranial sutures ultrasound, 14 children had positional plagiocephaly, 12 - metopic craniosynostosis, 18 - sagittal CS and one child had combined CS - a combination of metopic and right part of coronary sutures lesions. Thus, diagnostic imaging allowed to confirm metopic, sagittal and coronary sutures CS. Ultrasound was also performed in the postoperative period in the bone defect area to assess its and other cranial sutures fusion dynamics. The use of the algorithm and ultrasound protocol, in authors opinion greatly facilitates preoperative surgical planning and dynamic observation in the postoperative period. Conclusion: Cranial sutures ultrasound can be considered as an alternative method of instrumental CS diagnosis and patient postoperative management after endoscopic surgery. Described CS ultrasonic classification allows to use it for screening in the early stages of the disease.
Читать
тезис
|