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Название |
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Индекс цитирования |
Ссылка на источник |
Glucagon-like peptide-1 analogue liraglutide (Saxenda®): Mechanism of action, efficacy for the treatment of obesity
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01.01.2018 |
Romantsova T.
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Obesity and Metabolism |
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0 |
Ссылка
© 2018 Russian Association of Endocrinologists. All rights reserved. The development of effective methods of obesity treatment with the goal of preventing many associated diseases is among the priorities of modern biomedical research. In 2016 glucagon-like peptide-1 analog (GLP-1) liraglutide 3 mg (Saxenda®) was approved in the Russian Federation for the treatment of obesity. This review presents literature data on the effects of GLP-1 and liraglutide on appetite and body weight as well as an analysis of the effectiveness and safety of drug Saxenda based on the results of major clinical trials.
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Morbid obesity treatment in adults
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01.01.2018 |
Dedov I.
Melnichenko G.
Shestakova M.
Troshina E.
Mazurina N.
Shestakova E.
Yashkov Y.
Neimark A.
Birykova E.
Bondarenko I.
Bordan N.
Dzgoeva F.
Ershova E.
Komshilova K.
Mkrtumyan A.
Petunina N.
Romantsova T.
Starostina E.
Strongin L.
Suplotova L.
Fadeev V.
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Obesity and Metabolism |
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3 |
Ссылка
© 2018 Russian Association of Endocrinologists. All rights reserved. The presented paper is a third revision of the clinical recommendations for the treatment of morbid obesity in adults. Morbid obesity is a condition with body mass index (BMI) ≥40 kg / m2 or a BMI ≥35 kg / m2 in the presence of serious complications associated with obesity. The recommendations provide data on the prevalence of obesity, its etiology and pathogenesis, as well as on associated complications. The necessary methods for laboratory and instrumental diagnosis of obesity are described in detail. In this revision of the recommendations, the staging of prescribing conservative and surgical methods for the treatment of obesity are determined. For the first time, a group of patients with obesity and type 2 diabetes mellitus is selected, in whom metabolic surgery allows a long-term improvement in the control of glycemia or remission of diabetes mellitus.
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