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Ссылка на источник |
Granulation of Effervescent Ingredients for Optimization of Gastroretentive Properties of Floating Proroxan Prolonged-Release Tablets
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01.07.2018 |
Nifontova G.
Krechetov S.
Dolotova O.
Buyukli S.
Akhmetzyanova A.
Krasnyuk I.
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Pharmaceutical Chemistry Journal |
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0 |
Ссылка
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Research results supporting the manufacturing technology for floating prolonged-release oral tablets based on a hydrophilic matrix with the nonselective α-adrenoblocker proroxan are presented.Wet granulation of the effervescent ingredients with the matrix produced tablets with the required buoyancy lag-time, float time, and proroxan release kinetics.
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