Репозиторий Университета

Год публикации: Все года 2018 2019 2020

Название	Дата публикации	Коллектив авторов	Журнал	DOI	Индекс цитирования	Ссылка на источник
HBsAg levels as a guide for finite treatment duration of chronic hepatitis B HBsAglevel HBV Nucleosideanalogues Relapse	01.10.2019	Abdurakhmanov D. Ibragimov E. Rozina T. Nikulkina E. Mazurchik N.	Clinics and Research in Hepatology and Gastroenterology	10.1016/j.clinre.2018.12.007	0	Ссылка
The role of DNA-methyltransferases in the life cycle of hepatitis b virus and pathogenesis of chronic hepatitis b ChronichepatitisB DNA-methyltransferases Genotypes HBsAg HepatitisBvirus Methylation Transcription Y-H2AX	01.01.2018	Kostyushev D. Zueva A. Brezgin S. Lipatnikov A. Volchkova E. Maleyev V. Chulanov V.	Voprosy Virusologii		0	Ссылка © 2017 Izdatel'stvo Meditsina. All rights reserved. Chronic hepatitis B is caused by a persistent form of hepatitis B virus, covalentiy closed circular DNA (cccDNA). Stability of cccDNA is associated with intracellular localization of cccDNA and formation of minichromosome, regu-lated by epigenetic mechanisms. One of the key mechanisms in epigenetics is methylation of DNA on CpG islands. Expression levels of DNA-methyltransferases (DNMTs) in chronic hepatitis B patients were shown to be upregu-lated. Nevertheless, the role of DNMTs in the life cycle of HBV and their effects on the cell remain elusive. In this review, we discuss latest achievements on the role of DNMTs in chronic hepatitis B and HBV in vitro models. Читать тезис

Репозиторий Университета

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