Репозиторий Университета

Год публикации: Все года 2018 2019 2020

Название	Дата публикации	Коллектив авторов	Журнал	DOI	Индекс цитирования	Ссылка на источник
Assessing Ge-132 as an antioxidant in organic and water-containing media Antioxidants Cyclicvoltammetry DPPH EPR Ge-132 Germaniumsesquioxides HRMS UVspectroscopy	01.03.2018	Vishtorskaya A. Saverina E. Pechennikov V. Krylova I. Lalov A. Syroeshkin M. Egorov M. Jouikov V.	Journal of Organometallic Chemistry		3	Ссылка © 2018 The antioxidant activity of Ge-132 (2-carboxyethylgermanium sesquioxide, [(O 0.5 ) 3 GeCH 2 CH 2 COOH] n ), a widely used organic germanium dietary supplement, was assessed by cyclic voltammetry and through its interaction with a stable radical 2,2,-diphenyl-1-picrylhydrazyl (DPPH) monitored by UV-Vis and EPR spectroscopy in water, CH 3 CN, DMF, MeOH, and their mixtures with water. The results obtained by these methods are coherent in that Ge-132 can manifest its antioxidant activity only in the absence of water because the latter hydrolyses its Ge-O-Ge fragment responsible for quenching free radicals. Thus, contrary to a common use of Ge-132 as a water-soluble agent, it can act as an antioxidant solely in a lipid environment, which is important for understanding the mechanism of its biological activity. Читать тезис