Репозиторий Университета

Год публикации: Все года 2018 2019 2020

Название	Дата публикации	Коллектив авторов	Журнал	DOI	Индекс цитирования	Ссылка на источник
Modern notions concerning the mechanisms of nitrate tolerance development: Prospects of coenzyme Q10 administration CoenzymeQ10 Endothelialdysfunction Nitratetolerance Organicnitrates	01.01.2018	Abdullaev S. Kozaeva L. Medvedev O.	Eksperimental'naya i Klinicheskaya Farmakologiya		0	Ссылка © 2018 Izdatel'stvo Meditsina. All rights reserved. Organic nitrates are widely used in clinical treatment of cardiovascular diseases, but the problem of developing tolerance during long-term therapy remains urgent. The analysis of published works shows that the nitrate tolerance development is caused by various mechanisms, including disturbances in neurohormonal regulation of vessel tonus and biochemical pathways of realization of the nitrate effect. This review summarizes the current notions of the mechanisms of nitrate tolerance development and vascular changes during nitrate drug application and analyzes potential efficiency of using coenzyme Q10 for preventing the development of nitrate tolerance and nitrate-induced endothelial dysfunction. Читать тезис
Coenzyme Q10 in cardiovascular and metabolic diseases: Current state of the problem Cardiacproceduresandresuscitation Cardiactoxicity Cardiomyopathies CoenzymeQ10 Dyslipidemia Heartfailure Hypertension Ischemicheartdisease Metabolicsyndrome Myocardialinfarction Obesity Type2diabetesmellitus Viralmyocarditis	01.01.2018	Zozina V. Covantev S. Goroshko O. Krasnykh L. Kukes V.	Current Cardiology Reviews		3	Ссылка © 2018 Bentham Science Publishers. The burden of cardiovascular and metabolic diseases is increasing with every year. Although the management of these conditions has improved greatly over the years, it is still far from perfect. With all of this in mind, there is a need for new methods of prophylaxis and treatment. Coenzyme Q10 (CoQ10) is an essential compound of the human body. There is growing evidence that CoQ10 is tightly linked to cardiometabolic disorders. Its supplementation can be useful in a variety of chronic and acute disorders. This review analyses the role of CoQ10 in hypertension, ischemic heart disease, myocardial infarction, heart failure, viral myocarditis, cardiomyopathies, cardiac toxicity, dyslipidemia, obesity, type 2 diabetes mellitus, metabolic syndrome, cardiac procedures and resuscitation. Читать тезис

Репозиторий Университета

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