Репозиторий Университета

© 2018 Dynasty Publishing House. All rights reserved. The objective: To give a characteristic of body composition in adolescents with atopic bronchial asthma combined with overweight, and to determine the impact of its disorders on the degree of disease control. Patients and methods: Bioimpedance analysis of the body composition was performed in 168 adolescents aged 12-17 years, including 68 patients with mild bronchial asthma in the remission stage and in combination with overweight, 50 overweight adolescents without asthma and 50 healthy same-age peers. Bioimpedance characteristics were compared with the degree of controlling the symptoms of disease. Results: As has been found, adolescents with atopic bronchial asthma combined with overweight are characterised by significant changes in the body composition, which is manifest by higher fat tissue (on average 156.8 ± 21.3% with respect to the norm), total body water and extracellular fluid (127.0 ± 8.1% and 112.3 ± 5.9%, respectively), lower active cell (to 92.8 ± 10.2%) and skeletal muscle mass (to 96.9 ± 6.2%). The degree of the above disorders of body composition was higher in patients with incomplete asthma control. Conclusion: Disorders of body composition in adolescents with bronchial asthma reflect a decreased physical activity, shifts in water-electrolyte balance and protein deficiency. Worsening of body composition is associated with loss of asthma control.