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Sapphire shaped crystals for laser-assisted cryodestruction of biological tissues
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01.01.2018 |
Shikunova I.
Dubyanskaya E.
Kuznetsov A.
Katyba G.
Dolganova I.
Mukhina E.
Chernomyrdin N.
Zaytsev K.
Tuchin V.
Kurlov V.
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Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
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3 |
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© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only. We have developed cryo-applicators based on the sapphire shaped crystals fabricated using the edge-defined film-fed growth (EFG) and noncapillary shaping (NCS) techniques. Due to the unique physical properties of sapphire: i.e. high thermal, mechanical, and chemical strength, impressive thermal conductivity and optical transparency, these cryo-applicators yield combination of the tissue cryo-destruction with its exposure to laser radiation for controlling the thermal regimes of cryosurgery, and with the optical diagnosis of tissue freezing. We have applied the proposed sapphire cryo-applicators for the destruction of tissues in vitro. The observed results highlight the prospectives of the sapphire cryo-applicators in cryosurgery.
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