Isolation and characterization of Wad Medani virus obtained in the tuva Republic of Russia


  • Dedkov V.G.
  • Dolgova A.S.
  • Safonova M.V.
  • Samoilov A.E.
  • Belova O.A.
  • Kholodilov I.S.
  • Matsvay A.D.
  • Speranskaya A.S.
  • Khafizov K.
  • Karganova G.G.
Дата публикации:01.03.2021
Журнал: Ticks and Tick-borne Diseases
БД: Scopus
Ссылка: Scopus

Аннтотация

© 2020 Elsevier GmbH Wad Medani virus (WMV) belongs to the genus Orbivirus and is a poorly studied arbovirus with unclear medical significance. Presently, a limited number of WMV strains are characterized and available in NCBI GenBank, some isolated many years ago. A new WMV strain was isolated in 2012 from Dermacentor nuttalli ticks collected from sheep in the Tuva Republic, Russia, and sequenced using high-throughput methods. Complete coding sequences were obtained revealing signs of multiple intersegment reassortments. These point to a high variability potential in WMV that may lead to the formation of strains with novel properties. These new data on WMV can promote better understanding of: ecological features of its circulation; relationships within the genus Orbivirus; and the medical significance of the virus.


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