Аннтотация

Objective To evaluate the efficacy of the Memokath stent in managing recurrent bulbar urethral strictures. Materials and Methods This is an investigative pilot stage 2A study in patients with a recurrent bulbar urethral stricture who underwent a Memokath stent implant from January 2014 to January 2016 in a single high-volume centre for urethral reconstruction. The Memokath stent (Pnn Medical A/S, Kvistgaard, Denmark) is manufactured from nitinol, a biocompatible alloy of nickel and titanium, which is endoscopically placed. It has a 24Fr. outside diameter and is preloaded on a disposable delivery device. When correctly positioned, the stent is anchored by a warm water (55C) instillation which expands the proximal end of the stent from 24Fr to 42Fr .The stent was provided in lengths of 3 to 7 cm in 1 cm increments. Results Sixteen patients were included in the study. Median follow-up was 16 mo. In 7 patients (43.7%) the stent was removed within 1 year. The main adverse events were pain, encrustations, stones and recurrent strictures. Four patients (25%) were considered a success and 12 (75%) were failures. Study limitations include the small sample. Conclusion Memokath stent was deemed to be not clinically helpful and had significant side effects and therefore should not be considered a treatment option for men with bulbar urethral strictures.