Репозиторий Университета

Fibrolamellar hepatocellular carcinoma and pregnancy. Tactics of treatment


  • Ignatko I.
  • Afanas'eva N.
  • Snegovoy A.
  • Ryabchikov D.
  • Dudina I.
  • Golubenko E.
  • Matsneva I.
Дата публикации:01.01.2018
Журнал: Voprosy Ginekologii, Akusherstva i Perinatologii
БД: Scopus
Ссылка: Scopus

Аннтотация

© 2018 Dynasty Publishing House. All rights reserved. Hepatocellular carcinoma (HCC) is rarely diagnosed during pregnancy, its fibrolamellar variant (FHCC) is a specific form that is more often diagnosed in young women and is rarely associated with cirrhosis or chronic infection with hepatitis B or C viruses. Making a diagnosis at early stages is complicated by the fact that the α-fetoprotein (AFP) level is usually not enhanced, and symptoms develop only at advanced stages of disease. A clinical case of FHCC in a 27-year-old woman is presented, diagnosed at the 30th week of pregnancy after persistent dragging and spastic pains in the epigastric region. US detected a tumour with sizes 110 × 81 × 89 mm and foci in the lungs. Variants of treating such patients depending on tumour characteristics, pregnancy period and family preferences are discussed.


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