Аннтотация

© 2018, Dynasty Publishing House. All rights reserved. The article reviews scientific literature, current recommendations dealing with the topical problems of the incidence and methods of diagnosing H. pylori infection, including among the pediatric population. The authors of the article pay attention to different figures of the global prevalence of H. pylori, to the dependence of infection on many factors, among them low socio-economic status and educational levels, overpopulation, pollution of sources of drinking water. Based on the principles of evidence-based medicine, the article analyses the level of sensitivity and specificity of the main methods of identification of H. pylori, emphasizes that the sensitivity of serological diagnostic method does not depend on factors decreasing bacterial load, such as intake of proton-pump inhibitors (PPIs), antibiotics, bismuth preparations, and also on gastric haemorrhage and gastric metaplasia. The serological diagnostic method in pediatrics remains attractive due to its non-invasiveness and low cost. But the problem of looking for highly informative and non-invasive methods of diagnosing H. pylori infection remains topical and needs further research.