Аннтотация

© 2018 Izdatel'stvo Meditsina. All Rights Reserved. Subjective cognitive decline (SCD) is characterized by subjective complaints of patients about memory impairment and/or other cognitive functions accompanied by absence of significant changes during neuropsychological test. It is shown, that subjective cognitive decline may be a predictor of clinically significant cognitive disorder development to the extent of dementia. The primary aim of the research was the analyses of neuropsychological characteristics of patients with SCD depending on their age, gender, cardiovascular risk factors and their emotional affectivity. Materials and methods. The testing results of 150 patients (103 females, 47 males) aging from 45 to 59 and from 60 to 74 (66 patients) were analyzed in comparison with 92 healthy subjects of the same age. The research included clinical examination and application of scales and surveys, which estimate cognitive functions. Results. The most significant differences among healthy subjects were memory markers’ impairment as well as directory functions of the elder group. Patients with SCD additionally showed disorders of speech and constructive praxis deterioration. No significant differences in neuropsychological markers between SCD-positive and SCD-negative gender groups were not found. Comparison of patients with emotionally-affective disorder with healthy control of the same age did not reveal any significant difference. Either there was no influence of cardiovascular risk factors on neuropsychological testing indices. Conclusion. Analyses of possible age and gender factors accompanying emotionally-affective and cardiovascular changes that influence neuropsychological characteristics of patients with SCD showed the crucial meaning of age, being found in more indices of elderly people than the ones of the healthy group.