Аннтотация

© 2018, Dynasty Publishing House. All rights reserved. This review analyzes the role of viral miRNAs produced by representatives of the Herpesviridae subfamilies (including Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae) in the development of herpesvirus infection. In all three subfamilies, microRNAs are involved in the regulation of latency, i.e. transition of lytic to latent infection. In CMV and HHV-8, miRNAs play an important role in escaping innate immunity. Moreover, viral miRNAs can be transferred to non-infected cells via exosomes.