Аннтотация

© The Authors, published by EDP Sciences, 2018. We report on hybrid nanocomposite scaffolds on the base of cross-linked hyaluronic acid derivative with embedded upconversion nanoparticles (UCNPs). The unique photoluminescence properties of specially designed hydrophilic UCNPs enable visualization of hydrogel using NIR irradiation. Formation of scaffold structure can be produced by means of 3D printing or direct laser writing. For the first time, we present visualization of nanohybrid scaffolds in live small animal aiming to demonstrate new possibilities of their luminescent remote control for tissue engineering.