Репозиторий Университета

Wound healing by the use of scalpel and various radio-frequency cutting devices (A randomized experimental study)

  • Stupin V.
  • Manturova N.
  • Kogan E.
  • Smirnova G.
  • Polivoda M.
  • Silina E.
Дата публикации:01.10.2018
Журнал: International Journal of Pharmaceutical Research
БД: Scopus
Ссылка: Scopus


© 2018, Advanced Scientific Research. All rights reserved. An experimental study was performed on Wistar rats with the purpose of histological evaluation of the surgical wounds state and the processes of their healing using a conventional surgical scalpel and three radio wave devices with different operating frequencies (2.2 MHz, 2.64 MHz, 3.8 MHz). It has been established that in animals with wounds inflicted by the radio-wave at the highestworking frequency, there were statistically significant differences both in terms and in the mechanisms of wound healing. These benefits were in the absence of a blood clot in the wound after the incision, also in minimal necrosis of the operating wound and adjacent tissues, in the absence of leukocyte infiltration in the wound; early (from 3 days) reparation and epithelialization of tissues. These features contributed to a reduction in the timing of wound healing and the absence of scar formation.

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