Аннтотация

© 2018 Izdatel'stvo Meditsina. All Rights Reserved. Subtle cognithe decline (SCD) is characterized by patients 'complai?Us about their memory and other cognirixe fimctions that do not make difficult professional or social acth'ity. Clinical neuivpsychological research reveals some changes, which does not fit defiiution of mild cognitive impairment. SCD as well as subjective cognithe degradation can predict more severe cognitive disorder, including dementia. The primary aim of the research was to analyze neuropsychological features of middle-aged and elder patients who sufferfrom SCD. PatietU groups were based on age, cardiovascular risk factor and the state of emotional condition. Material and methods. We analyzed the data of320patients, including 234 women and S6 men of45-59, 60-74, 75-S9 age groups. These results were compared to 104 healthy subjects of the same age groups. The research included clinical and neuropsychological evaluation of cognith'e fiinctions and emotional status. Results. The most significant differences between healthy subjects and the ones with SCD of various age groups were memory scores and executive functions as well as decline in Mini mental state examination and Frontal Assessme?it Battery. The dif-ferences in age connected cognitive status ofpatients with SCD and healthy ones were found. The comparison ofpatients with mild and subtle anxiety disorders with patie?its without emotional disorder of the same age has not revealed any significant differences. It was found that cardiovascular riskfactors influence frontal managing functions. C onclusion. The collected data confirm SCD specification amongpremild cognitive functions and decline show the peculiarities of age connected cognitive status as well as absence of negative connection between emotional disorder.