Аннтотация

© 2018 Dynasty Publishing House. All rights reserved. The review deals with specificities of interactions between decidual cells and cells of the maternal immune system. Literature data about involvement of decidual cells in initiation of the immune process are presented. The role of decidual cells in the formation of immunological tolerance due to variously secreted and expressed cytokine molecules that control sequential reproductive events has been shown. In the decidual membrane, complex interaction between decidual cells and cells of the maternal immune system occurs, aimed at ensuring immunological tolerance of the «mother-fetus» system. Impairment of this process leads to the development of gestational complications, including loss of a pregnancy.