6 Декабря 2018
Neurobiologists from Sechenov University specified functions of a gene autism-associated

Neurobiologists from Sechenov l University confirmed that stress in early age affects the mice with activated and deactivated CDH13 gene in different ways. 


Different variants of this gene are associated with the development of ASDs, ADHD, and depression. The discovery would help specify the role of genetics in the development of neuropsychiatric disorders. The discovery would help specify the role of genetics in the development of neuropsychiatric disorders. The results of the study were published in the Progress in Neuro-Psychopharmacology & Biological Psychiatry journal.
According to the tests, the animals without cadherin 13 were different from conrols with the normal CDH13 function. Early exposure to stress, such as short-term separation from the mother, usually makes the mice more stress-resistant in adult age, and this was confirmed by the behavior of the mice with the working gene.  

The results of the study were published in the Progress in Neuro-Psychopharmacology & Biological Psychiatry journal. The participants of the study also represented the University of Würzburg (Germany) and Maastricht University (The Netherlands).

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